Starch usually not hydrolyzed. Gelatin not liquefied. Sodium hippurate not hydrolyzed. Pyrrolidonearylamidase & Voges-Proskauer
reaction negative.  Esculin usually split. Ammonia produced from arginine. Alkaline phosphatase variable.
Acid produced from glucose, maltose, lactose, sucrose, trehalose & salicin.
Arabinose, ribose, xylose, glycerol, mannitol & sorbitol are not fermented.
Streptococcus sanguinis
Taxonomy
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Firmicutes => Bacilli => Lactobacillales => Streptococcaceae => Streptococcus => Streptococcus sanguinis  (White and Niven 1946)
Trüper and De' Clari 1997. Old synonym:
S. sanguis  White and Niven 1946.
Lancefield group H or non-groupable.
Gram positive cocci, 0.8-1.2 μm in diameter, grouped in short to  long chains, non-
motile. May show occasional rod-shaped cells in aerobically growth cultures.
Most strains produce  alpha-reaction on blood agar (but one strain produced
narrow-zone beta hemolysis) and pronounced greening on chocolate agar.
Matt or glossy type colonies may be produced, usually 0.7 to 0.9 mm in diameter on
blood agar after 48 hours at 37 °C.
Growth at 37 °C, no growth at 10 °C, growth at 45 °C is variable.
Fails to grow in presence of 6.5 per cent NaCl or in skim milk containing 0.1 per cent
methylene blue. Most cultures grow on blood agar containing 40%  bile. Final pH in
glucose broth, between 4.6 and 5.2.
Isolated from the blood stream or "heart vegetation" of endocarditis in humans. Occasionally isolated from infected sinuses and teeth
and from house dust.
May be a cause of subacute bacterial endocarditis.
  1. J. G.Holt et al., 1994.Bergey’s Manual of Determinative Bacteriology, 9-edition, Williams & Wilkins.
  2. Truper H.G. & De' Clari L.: Taxonomic note: Necessary correction of specific epithets formed as substantives (nouns) "in
    apposition". Int. J. Syst. Bacteriol., 1997, 47, 908-909.
  3. White J.C. & Niven Jr. C.F.: Streptococcus s.b.e.: a streptococcus associated with subacute bacterial endocarditis. Journal of
    Bacteriology, 1946, 51, 717-722.]
  4. Kilian M., Mikkelsen L. & Henrichsen J.: Taxonomic study of viridans streptococci: description of Streptococcus gordonii sp.
    nov. and emended descriptions of Streptococcus sanguis (White and Niven 1946), Streptococcus oralis (Bridge and Sneath
    1982), and Streptococcus mitis (Andrewes and Horder 1906). Int. J. Syst. Bacteriol., 1989, 39, 471-484.
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