Taxonomy
Morphology
Cultural characteristics
Biochemical characters
Ecology
Pathogenicity
References
Firmicutes => Bacilli => Lactobacillales => Streptococcaceae => Streptococcus => Streptococcus mitis Andrewes and Horder 1906.
Lancefield group O (biovar 1), K or non-groupable.
Gram positive cocci, 0.6-0.8 μm in diameter, arranged in long chains, non-motile.
S-type, sometimes R-type colonies, alpha-haemolytic. Rarely mucoid colonies may
occur or colonies resembling broken glass.
Facultatively anaerobic, growth at 37.0 °C. Growth at 45 °C is variable.
Growth on : trypticase soy agar with defibrinated sheep blood., brain heart infusion
broth. Most strains may require some factors from yeast extract for growth.
Isolated from human saliva, sputum & feces.
Oral & pharynx normal inhabitant. May cause septicaemia, endocarditis or meningitis in immunosuppressed organisms.
- Andrewes F.W. & Horder T.J.: A study of the streptococci pathogenic for man. Lancet, 1906, 2, 708-713
- Elliott, John A., Burke, John P., Classen, David C., Ford, Clyde D., Evershed, Sherri, Aloia, Mary R., Wilfahrt, James K.:
Streptococcus mitis sepsis in bone marrow transplant patients receiving oral antimicrobial prophylaxis. American Journal of
Medicine, 1990.
- Balkundi, Dhruv R. M.B., B.S., M.R.C.P.; Murray, Dennis L. M.D.; Patterson, Maria J. M.D., Ph.D.; Gera, Renuka M.D.; Scott-
Emuakpor, Ajovi M.D., Ph.D.; Kulkarni, Roshni M.D.: Penicillin-Resistant Streptococcus mitis as a Cause of Septicemia with
Meningitis in Febrile Neutropenic Children
Acid is produced from glucose, lactose, maltose & sucrose. Variable reaction for
trehalose, inulin, raffinose, salicin, sorbitol. Acid is not produced from arabinose,
xylose, glycerol & mannitol.
Voges-Proskauer, catalase, hydrolysis of hippurate, pyrrolidonearylamidase &
beta-glucuronidase negative.
Hydrolysis of esculin, alpha & beta-galactosidase, alkaline phosphatase, ADH
variable.
(c) Costin Stoica